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However, research on bacterial carriers is still in the preclinical stage, and much effort is still needed to address some scientific issues before the translation to the clinic can be truly accomplished

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It is estimated that an adult human (mean weight, 70 kg) with moderate coffee intake consumes approximately 400 mg of caffeine per day, which is equivalent to 6 mg/kg per day or three cups of coffee

doi: 10.1111/j.1365-2133.2010.10147.x, PMID: [DOI] [PubMed] [Google Scholar] 75.Tsotra K, Garoufi A, Kossiva L, Gourgiotis D, Tsoukatou T, Katsantoni E, et al