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PFOS reduced the phosphorylated levels of mTOR and AKT and induced autophagy activation

P., & Gijsen, A

However, other psychological symptoms (anxiety, depression, irritability), arousal (drowsiness), neurologic symptoms (photophobia), and cranial parasympathetic symptoms (lacrimation), as well as general symptoms (e.g., yawning, increased urination, nausea, diarrhea, and food cravings), can precede the onset of pain [61,62]

Journal of Muscle & Nerve 1991;14:598-604

10.1016/S1474-4422(18)30500-3 4