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The iodide salt is polar, but working stocks are typically prepared in DMSO or ethanol, then diluted into aqueous buffers
Even if it is insensitive for detecting nephrotoxicity, this test is suitable at the individual level to exclude confounding factors accounting for increased excretion of plasma proteins (e.g., leukocyturia, haematuria, or bacteriuria)
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DOI: 10.1021/acs.jcim.0c00025 19
A 2022 reference values study in 346 healthy adults aged 18-85 established normative ranges
