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doi: 10.1016/j.jad.2020.03.029
#GlutaChemistry #ReducedGlutathione #GSH

Fu H, Chen Z, Josephson L, Li Z, Liang SH

[DOI] [PubMed] [Google Scholar] 67.Blatt S, Voelxen N, Sagheb K, Pabst AM, Walenta S, Schroeder T, et al

The fate of the luminal GSSG generated is unclear

This rapid GSH loss disrupts redox homeostasis, promotes ROS accumulation, and facilitates redox-dependent protein modifications that drive apoptotic commitment