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NS-EM images of the SEC-purified complexes showed that the nanoparticles are ~35 nm in diameter and in the 2D class averages the I53-50 nanoparticle core and protruding E2E1 densities were clearly visible (Fig

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In addition, macrophages also release pro-fibrotic molecules such as transforming growth factor- (TGF-), that is crucial in the initiation of the fibrotic process [24, 25]