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These results underscore a pivotal role for mPFC-derived CCK in shaping affective responses to social stress and suggest a promising molecular target for intervention in stress-related neuropsychiatric disorders

This is mechanistically different from acetylcholinesterase inhibitors or dopamine modulators: Dihexa doesn't boost existing neurotransmitter levels

On the other hand, ferroptosis can directly impair the antitumor immune response by negatively affecting key immune cells, including natural killer (NK) cells, B cells, cytotoxic T cells, and antigen-presenting cells (APCs), which are critical components of antitumor immune defense
No Therapeutic Use Exemption pathway exists since AOD-9604 has no approved therapeutic indication

The intervention group, which participated in a 4-week program of supervised physical exercise, including aerobics, strength training, and Nordic walking, showed significant improvements in the 6-min walking test (6MWT), standing up and walking test, and spirometry values such as FEV1 and FEV1/FVC
