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Inhibition of constitutively activated phosphoinositide 3-kinase/Akt pathway enhances antitumor activity of chemotherapeutic agents in breast cancer susceptibility gene 1-defective breast cancer cells

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Zileuton-fed mice develop fewer intestinal polyps and exhibit a significant reduction in systemic and polyp-associated inflammation (105)

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J Pharmacol Sci 108:227238 Massucci FA, DiNuzzo M, Giove F, Maraviglia B, Castillo IP, Marinari E, De Martino A (2013) Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective
