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The high metabolic demands of stria vascularis, sensory hair cells, and spiral ganglion neurons (SGNs) render these structures susceptible to the detrimental effects of ROS

Although nucleoids are distributed throughout the mitochondrial matrix, they are often located in the proximity of the cristae, which carry the OXPHOS system

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Note, when the above RBC morphologic abnormalities (keratocytes, schistocytes, acanthocytes, spherocyte-like cells) are seen in low numbers in an anemic animal, they are unlikely to be the cause of the anemia, e.g