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Description
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF-1/HMGB1 signaling pathway
Inter J Infect Dis

2010;298:C38C45

Clinical signs of this pathology include resting tremor, rigidity, and bradykinesia, which are made evident by the loss of about 80% of striatal dopamine and 50% of nigral neurons (Fearnley and Lees, 1991)

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