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Another retinoic acid analogue, 13-cis-retinoic acid exhibited modest therapeutic efficacy in recurrent GBM patients [69]
doi: 10.1016/j.metabol.2009.09.036
BCL2 inhibition by BH3 mimetic can trigger ROS generation to amplify apoptosis in cancer cells [116]
Some of these dogs also showed clinical signs suggestive of enteropathy, such as diarrhea and a failure to gain weight
Therefore, the potential clinical application of exometabolome findings is evident and warrants further investigation (Moreno-Torres et al., 2022a)
