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Revisiting Vitamin B12 Deficiency: A Clinicians Guide For the 21st Century Low Plasma Vitamin B12 Is Associated With Lower BMD: The Framingham Osteoporosis Study Clinical manifestations and diagnosis of vitamin B12 and folate deficiency Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency (Review) Mentioned in This Article: Vitamin B12 Vitamin B12 is essential for red blood cell formation and DNA production

then examined a cohort of 80 patients, split equally into 4 groupsone receiving lidocaine injections, one receiving 100 mg thiamine subcutaneously, one receiving 1000 g cobalamin B12 subcutaneously, and one receiving a combination of thiamine 100 mg and B12 1000 g subcutaneously

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There was no history of smoking, alcohol, or illicit drug use and no family history of blood disorders

Heart tissue samples were weighed, homogenized with 8 times of 2.5 mM ammonium acetate in methanol, and 20 L of the extraction from each sample was used for the assay