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Moreover, the gut microbiome, an essential player in maintaining redox balance, is adversely affected by these same factors, diminishing its ability to contribute to our antioxidant defenses

(See Table 1)

That might mean vitamin D for a deficiency, iron for anemia, omega-3s for cardiovascular health, or probiotics for a digestive condition

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In short, the choice of derivatizing agent depends on analyte characteristics and scientific goals, with comprehensive MALDI-MS derivatization strategies available elsewhere