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Whether through externally applied stimuli (ultrasound, light, magnetic fields) or intrinsic catalytic reactions, these modalities are designed to concentrate cytotoxic agentssonosensitizers, photosensitizers, thermal converters, or Fenton catalystswithin the acidic, enzyme-rich lysosomal lumen

(10) Research suggests that deficiencies of vitamin B12 can decrease energy and exercise tolerance, along with causing fatigue and shortness of breath

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