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Highlights of mTOR and KG structure and functions Mechanistic target of rapamycin is a serine/threonine protein kinase of the phosphatidylinositol-3-kinase-related kinase (PIKK) family that is the basis of two functionally distinct multiprotein complexes: rapamycin-sensitive complex 1 (mTORC1) and relatively rapamycin-insensitive complex 2 (mTORC2)

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Combined with possible features of peripheral neuropathic pain including burning, paresthesia, hyperalgesia, and allodynia, the origin of pain may, in a certain proportion of people, stem from the peripheral nervous system