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[DOI] [PubMed] [Google Scholar] 198.Sins J.W.R., Fijnvandraat K., Rijneveld A.W., Boom M.B., Kerkhoffs J.L., van Meurs A.H., De Groot M.R., Heijboer H., Dresse M.F., Ferster A., et al

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Ongoing research aims to understand how these peptides might affect neurotransmitter levels, neuroprotection, and cellular regeneration

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Methods: NNT was calculated for eight stroke clinical rials/meta-analyses purposively selected to include small, moderate and large treatment effects and diverse treatment types, including thrombolysis (NINDS tPA, IST3), thrombectomy (HERMES, AURORA, Large Core EVT), surgery for AIS (Hemicraniectomy), surgery for ICH (ENRICH), and blood pressure control (OPTIMAL BP)

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As these therapies should confer multi-organ benefits, this may be circumvented by utilizing composite endpoints combining CV and non-CV events

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