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First, optimal dosing in humans remains undefined, with current practice based primarily on extrapolation from animal studies and anecdotal clinical experience rather than formal dose-finding studies

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

[DOI] [PubMed] [Google Scholar] [125].Deutsch M, Graffeo CS, Rokosh R, Pansari M, Ochi A, Levie EM, Van Heerden E1, Tippens DM1, Greco S1, Barilla R1, Tomktter L, Zambirinis CP, Avanzi N, Gulati R, Pachter HL, Torres-Hernandez A, Eisenthal A, Daley D, Miller G

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As Hancock explains it, the idea of boosting your immunity is a bit of a marketing ploy dreamed up by the "health food guys," but that doesn't mean there's no truth in it
