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A qualified provider will always tailor this schedule to your specific B12 levels and health goals

Additionally, the harsh acidic environment of the stomach and/or dysfunctions in R-proteins (haptocorrins) that protect B12 in the stomach, and potential degradation by gastric enzymes can compromise the stability and bioavailability of oral B12 supplements

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doi: 10.1126/science.aat5314 418 PoonDCHoYSChiuKWongHLChangRC
They observed that insulin was well tolerated but did not positively affect cognition, function, or mood after IN administration

For confirmed deficiency or pernicious anaemia, NICE Clinical Knowledge Summaries recommend hydroxocobalamin 1mg intramuscularly, with frequency determined by the underlying cause and neurological involvement
