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According to ANOVA, the central composite design was suitable for dependent responses, since the values of R 2 for particle size, PDI, ZP, and EE were, respectively, 0.815, 0.725, 0.932, and 0.73

Interestingly, external iron supplementation has been shown to inhibit M1 polarization by downregulating proinflammatory mediators and iNOS expression through STAT1 inhibition, without impairing phagocytic capacityM1 (108)

10.1007/s00726-013-1500-6 44 WuJ.RajuB.ZhaP.GongH.RenY.LiZ.et al (2023)

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