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Problems with the WHI Study The WHI study had several issues that impacted its findings and interpretation: Selection Bias: All women with menopausal symptoms were excluded from the study

The term melena is used to describe this finding

Some pharmacies use methylcobalamin instead of cyanocobalamin, which is a different form of B12 with slightly different pharmacokinetics

dosing from unregulated online sources is unverified
Low levels of B12 can affect neurotransmitters, such as serotonin and dopamine, which help regulate mood
