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The gasping syndrome and benzyl alcohol poisoning

Hughes C, Faurholm B, DellAccio F, Manzo A, Seed M, Eltawil N, et al

A miscalculation of even 10-20% can mean the difference between a therapeutic dose and a dose that triggers unnecessary side effects or provides inadequate results

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Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo

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