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Renal tubulointerstitial hypoxia: cause and consequence of kidney dysfunction

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After starvation for 6 h, the cells were left untreated or stimulated with 0.2 nM human recombinant EGF in the presence or absence of the indicated concentrations of gefitinib or aML5-PEG3 for 5 min

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251,252 As a consequence, the vascular architecture of the kidney fails to be maintained with reductions in capillary number as well as individual capillary caliber and area

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