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Topical peptides are useful for certain applications (GHK-Cu copper peptide has reasonable evidence for topical activity), but for the major therapeutic peptides growth hormone secretagogues, BPC-157, Epithalon systemic delivery is required to produce the effects seen in the research literature

BPC-157 is an unregulated research compound with plausible mechanisms and no human RCTs in PCOS populations

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This approach may help support the bodys natural response while reducing the risk of reduced sensitivity over time