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Comparison of RNAseq datasets To enable a meaningful comparison of datasets, we use a customized ranking factor (RF), defined as: This approach combines both the magnitude of gene expression change (log 2 fold change) and the statistical significance (adjusted P -value) into a single metric, providing a more robust measure of gene importance
Several types of selective autophagy, such as ferritinophagy, clockophagy, lipophagy, and mitophagy, promote ferroptotic cell death through degradation of the iron-storing protein ferritin, the core circadian clock protein aryl hydrocarbon receptor nuclear translocator-like (ARNTL, also known as BMAL1), LDs, and mitochondria, respectively (Hou et al., 2016
2019]Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation
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