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Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

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For instance, the observed mitigation of microgliosis and pro-inflammatory cytokine release could be directly investigated by co-culturing our hCiPSC-NSCs or their conditioned medium with activated microglial cells (e.g., BV-2 cell line or primary microglia stimulated with LPS/ATP)

Its levels can be depleted, and replenishing them with standard supplements is less effective if your body isn't absorbing them well

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