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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Ren X, Ren L, Wei Q, Shao H, Chen L, Liu N

Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment

Such changes may be caused by the decline of neurotrophic factors, such as brain-derived neurotropic factor (BDNF), nerve growth factor (NGF), and glia-derived neurotropic factor (GDNF) (44)

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Garner JP, Gaskill BN, Weber EM, Ahloy-Dallaire J, Pritchett-Corning KR

doi:10.1110/ps.035352.108