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Addressing these hurdles is crucial for enhancing miRNA therapys effectiveness by improving its pharmacokinetic and pharmacodynamic properties 124,125
Dysbiosis and increased intestinal permeability (leaky gut) may amplify neuroinflammatory state of the brain, further justifying the need for research into interventions combining metabolic and microbiota-based therapies
1), which accounts for about 40% of T4 turnover, while thyroidal secretion of rT3 is negligible
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