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(Erstad 2022) If seizures persist, an additional 20 mg/kg IV (max 1500 mg) may be administered over 5 minutes

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Pharmacokinetic Profile Fernandez-Perez et al

Oxalate oxidase found mainly in higher plants, catalyzes the degradation of oxalate to CO 2 and H 2 O 2 , and its main function is to promote seed germination and defend against pathogenic bacteria 22,23

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All cited studies are conducted in cellular or rodent systems consistent with RUO classification