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Inactivation of GPX4 through depletion of GSH with erastin, or with the direct GPX4 inhibitor (1 S ,3 R )-RSL3 (hereafter referred to as RSL3), ultimately results in overwhelming lipid peroxidation that causes cell death (Table 1)

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Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

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The clearance time courses for dihexa and the standards fit curves defining single-phase exponential decay processes with R 2 values between of 0.96 and 0.99 (Supplemental Fig