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Do not use the remaining solution

Toxicol Sci 57:338344 Deneke SM, Lynch BA, Fanburg BL (1985) Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity

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In the recent Rome Proposal, a COPD exacerbation was described as an event characterised by an acute burst of airways inflammation due to stimuli (e.g., bacteria, viruses, or environmental pollutants) that is coupled with worsening of existing airflow limitation, leading to worsening symptoms (dyspnoea and/or cough and sputum), which may be accompanied by tachypnea and/or tachycardia [4]

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doi: 10.7759/cureus.2582
