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Yes, it dilutes its effectiveness but makes it less irritating, too
It binds to GHRH receptors in the pituitary gland and encourages the pituitary to release growth hormone in a pulse-like pattern

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:( Even in that case you are probably fine because as far as we know it cannot penetrate the skin

Weber T Recent Advances in Re-Engineering Modular PKS and NRPS Assembly Lines

Oral supplements have to travel through your entire digestive system, where a lot can get in the way of proper absorption