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However, some natural compounds, such as 8 alkaloids [berberine hydrochloride (Zhu et al., 2019a), berberrubine (Yu et al., 2018), coptisine (Wang et al., 2021a), dihydroberberine (Li et al., 2021), evodiamine (Shen et al., 2019), matrine (Yan et al., 2020), nigakinone (Liu et al., 2023), and piperine (Qu et al., 2021), licochalcone A (Zhang et al., 2021), licoflavone B (Zhang et al., 2022b), phloretin (Zhang Z

Previous studies indicated that zinc deficiency upregulates the activity of NF-B [80], while zinc supplementation suppresses its activity in ECs [69]

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Haber SL, Awwad O, Phillips A, et al

Immune infiltration analysis using CIBERSORT algorithm, consensus clustering for molecular subtyping, and competing endogenous RNA (ceRNA) network construction were conducted to explore regulatory mechanisms