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Carnitine is made in the body from the amino acids lysine and methionine, and requires the breakdown of over 30 grams of muscle protein to produce 1 gram of carnitine

J.Reprod.Infertil 2010;10(4):245-251

B vitamins, zinc, iron, and omega-3 fatty acids play a crucial role in skin barrier integrity and supporting skin cell renewal

Yadav KS, Rajpurohit R, Sharma S

Electrophysiological disturbances may arise as a consequence of these structural and biochemical changes

The OAD can result from mutations in genes encoding enzymes of fatty acid metabolism, enzymes of amino acid metabolism, and enzymes involved in several other metabolic pathways such as the TCA cycle