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doi: 10.1128/MCB.24.12.5434-5446.2004 [DOI] [PMC free article] [PubMed] [Google Scholar] 166

Additional in vitro studies revealed that overexpression of 15-LOX in mesenchymal stem cells increased LXA4 production and modulated the Th17/Treg balance toward an anti-inflammatory Treg phenotype [144]

Popovich, and Mark A

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Senescence surveillance is initiated by the SASP that activates immune cells to clear senescent cells preventing tumor initiation (167), where both macrophages and NK cells have an important task (192, 193)

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