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Description
doi: 10.1155/2022/3567879 142

19 Under oxidative stress, the glutathione (GSH) level in cardiomyocytes decreases by 6070%, and the levels of Gln, glutamate and -ketoglutarate (-KG) also decrease significantly, while the enzyme activity of GLS, which converts Gln to glutamate, is enhanced

By acting as an electron donor, glutathione reduces any disulfide bond formed within cytoplasmic proteins to cysteines
N -acetylcysteine has shown promising results in populations with these disorders, including those in whom treatment efficacy has previously been limited
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