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46 In the rare instances that medication cessation does not lead to cholestasis resolution, cholestyramine or ursodeoxycholic acid has been used, followed by rifampicin and opioid antagonists if the first-line agents fail

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The extracted information pertained to the characteristics of the trials (i.e., publication year, infertility duration, sample size, first authors name, study setting, and dosage of LC supplement) and the demographics of the patients (e.g., sex, body mass index [BMI], and age)

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Once released, all- trans -retinal is converted to all- trans -retinol, which returns across the interphotoreceptor matrix to the retinal pigment epithelium, completing the visual cycle

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