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PMID: 40507030

The human gastrointestinal flora can be roughly divided into three main groups according to their different functions within the host: physiological bacteria, which account for more than 90% of the total and have nutritional and immunomodulatory roles

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However, human-based research is limited

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Indeed, it was recently reported that treatment of cells with H 2 O 2 , which can lower GSH levels, leads to increased expression of NRF2 target genes in a KEAP1-independent mechanism 69