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Clack CTM, Choukulkar A, Cot B, McKee SA

(134) described that BAPs mastoparan M (Mast-M) extracted from wasp venom could inhibit the MAPK/NF-B signaling pathway and reduce oxidative stress, thereby blocking the activation of the NLRP3 inflammasome and effectively treating gouty arthritis

Compound: AOD-9604

However, in the presence of oxidative or nitrosative stress, GST can form homodimers that alter the reduced states of cysteine residues in its structure, resulting in JNK dissociation from the GSTJNK heterocomplex and causing subsequent activation of the c-Jun protein

Nutrients 16:702