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Here, we used genetically encoded redox probes (roGFP2 and roGFP-iL), targeted to the periplasm, to directly probe the thiol redox homeostasis in this compartment
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As these misshapen cells struggle to exit the bone marrow into the bloodstream, there are fewer healthy red blood cells to carry oxygen around the body
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However, the pathomechanisms underlying the disease remain incompletely understood
