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Dietary vitamin E supplementation enables rapid vitamin accumulation in lung tissue and mitigates amiodarone-induced elevation of TGF- and hydroxyproline levels, thereby preventing lung tissue damage

Yet genetics highlight PIF4s privileged rolewithin the PIF quartet (PIF1, PIF3, PIF4, and PIF5), only loss of PIF4 markedly dampens thermosensory hypocotyl elongation, whereas single knockouts of the others have minimal effect 7,93

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Diverse routes and methods for synthesizing ALA have been described in the literature, including racemic synthesis, chemical and enzymatic resolution synthesis, asymmetric chiral pool synthesis, asymmetric chiral auxiliary synthesis, enzyme-catalyzed asymmetric synthesis, chemical-catalyzed asymmetric synthesis

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