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Note, in general, since the beginning, the concept of cytoprotection did not consider the neurotransmitter activity as the basis for the cytoprotective effects of the implemented agents (i.e., prostaglandins [16,17], sulfhydryl [141], somatostatin [142], dopamine [143])

Side effect management is crucial for adherence and success

Epitalon appears to partially restore pineal function, acting as a true circadian regulator capable of re-entraining disrupted biological rhythms

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mRNA expression studies at 1 and 24 hr, provided strongly elevated ( Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos3, and Nos1 ) and decreased ( Nos2, Nfkb ) gene expression ( Mapk1 not activated), as a way how BPC 157 may act

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