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Chen et al., 2016a,b)

Neuropathic Pain: the Dysfunction of Drp1, Mitochondria, and ROS Homeostasis

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Kwon and co-authors used homoplasmic lettuce cell lines to express codon optimized FVIII protein, which resulted in high level expression of CTB fused FVIII HC, light chain (LC: A3, C1 and C2 domains), C2 domain and the entire BDD human FVIII protein (SC) in chloroplasts to levels required for clinical translation [52]
