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Introduction Schizophrenia (ScZ) is a severe mental illness associated with pronounced cognitive and sensory impairments that are thought to emerge from underlying impairments of neural circuits ( Recent evidence has implicated a disturbance in the balance between excitation and inhibition (E/I-balance), a mechanism that assures efficient information transfer in neural networks ( Evidence for E/I-balance abnormalities in ScZ comes from post-mortem studies that have examined alterations in GABAergic interneuron properties as well as N-methyl-D-aspartate receptor (NMDA-R) density

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