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Interestingly, as -arrestins function as physical and biochemical scaffolds that anchor and recruit endocytic machinery as well as components of the MAPK pathway to endosomes, it is possible that -arrestins may limit ERK translocation to the nucleus, thus promoting cytoplasmic ERK signaling (Bond et al., 2019)

Immunosuppressants like mycophenolate and azathioprine dial down immune activity, yet they do not restore balance

Animals were administered with either TAT or TAT-DAT NT (at the dose of 0.4 nmol

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Experimental data also propose that Epithalon may modulate histone-DNA interactions, potentially altering chromatin accessibility and influencing transcription processes