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Neurogenesis is also likely affected by the downregulation of the T-box gene Tbr2/EOMES at this early stage of organoid development, as it is highly expressed in intermediate cortical progenitors in mice (Mihalas and Hevner, 2017) and humans (Cipriani et al., 2016) as part of a transcriptional cascade during glutamatergic neurogenesis

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[DOI] [Google Scholar] Williams L

VPA-Induced ASD Model Group In the ASD model, significant genus-level alterations in the gut microbiota were observed (Figure S2A)
