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Supporting this, reanalysis of published datasets revealed reduced fat-7 expression in several mitochondrial mutants with activated UPRmt, including clk-1, cco-1 , and hsp-6 (Fischer et al, 2014

March 2024

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For example, the FPR2 synthetic peptide agonist WKYMVm reduced the accumulation of myofibroblasts and macrophage infiltration in the bleomycin model of skin fibrosis ( in vitro cultured human synovial fibroblasts ( The anti-fibrotic actions of several specialized pro-resolving mediators (SPMs), which are bioactive molecules produced from essential polyunsaturated fatty acids, have also been tested using in vitro and in vivo models

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Abstract Fibromyalgia, a chronic pain condition marked by abnormal pain processing, impacts a significant part of the population, leading to reduced quality of life and function