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In murine models of allergic airway inflammation, melatonin reduced eosinophilia, type 2 cytokine production, and airway hyperreactivity without altering ILC2 abundance

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Western blot analysis of thoracic aorta proteins showed that the classic aging markers P21 and P16 were significantly downregulated following FOXO4-DRI treatment, whereas the expression levels of the cell proliferation marker Ki-67 and Lamin B, a key protein involved in nuclear structural stability, were markedly upregulated (Figure 1A)

[1] Dual-Compound Research Findings: Co-administration of Cagrilintide with GLP-1 analogs has been shown to produce stronger effects on energy and glucose regulation markers in preclinical studies, supporting its value in combination research