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Common Contraindications Active or recent cancer (BPC-157 and TB-500 angiogenesis concern), Wilson's disease or other copper metabolism disorders (GHK-Cu component), pregnancy or breastfeeding (no safety data for any component), and competitive sport at WADA-tested levels (BPC-157 and TB-500 are listed under WADA category S0 Unapproved Substances) are commonly cited reasons not to research KLOW

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Studies involving in vitro and in vivo models, as well as the first-in-human clinical trial, have assessed the efficacy and safety of mitochondria isolated from human umbilical cord mesenchymal cells [361]
