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The combination of senolytics and senomorphics could rejuvenate both bone and muscle tissue by eliminating senescent cells and modulating the inflammatory environment that promotes bone resorption and muscle wasting.215 Such therapies could reduce the risk of fractures, improve muscle strength, and enhance mobility in the elderly.216 Cancer: Cellular senescence is a double-edged sword in cancer

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Furthermore, it downregulated the gene expression of pro-inflammatory cytokines such as IL-1 and TNF- (106), implying that magnesium not only independently regulates glucose and lipid metabolism but also displays synergistic effects with other nutrients to ameliorate inflammatory and OS

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Nature (1999) 402:65660