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[22] In the current classification of the pathogenesis of IPF, it is believed that it occurs by way of the formation of a UIP (usual interstitial pneumonia) lesion, which then undergoes the aforementioned pathological condition characteristic of IPF

Furthermore, there are adverse effects that can span the duration of KD therapy, which frequently include gastrointestinal disturbances, including constipation, abdominal pain, emesis, and gastroesophageal reflux disease

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These NAD + -dependent deacetylases regulate mitochondrial biogenesis through transcriptional players such as the peroxisome proliferator-activated receptor gamma coactivator 1- (PGC-1), as well as pathways involved in DNA repair and redox balance [253, 254]

Studies using either transformants overexpressing GSH biosynthesis genes or GSH-deficient mutants revealed significant breakthroughs in our understanding of GSH in plants metabolism