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Comparison of hydroxocobalamin and cyanocobalamin in the treatment of pernicious anaemia

Lee K, Hong Y, Choi J, Lee SH, Kim TH

If the FDA were to reclassify any of the removed Category 2 substances into Category 1, compounding pharmacies would be able to resume lawful use of those substances under the interim policy without waiting for completion of the formal rulemaking process

The compound's stability in properly formulated products, combined with its gentle nature and low irritation potential, makes it ideal for both leave-on and rinse-off applications

Clin Psychiatry 2015;1005:394-6

It prohibits specific formulations, marketing claims, and delivery methods that cross from supplement territory into unapproved drug territory